Skip to main content

Where to find accurate information on news about drugs for Alzheimer's disease

The recent publication of a clinical trial for a drug (Aducanumab) being developed to treat Alzheimer's disease has hit the mainstream media big time. In all of this commotion, especially when the reporting may not have been written by someone familiar with the field, it can be easy for people to get swept away by the huge media buzz and feel like "this is it! the new wonder drug everyone has been waiting for is finally here!" 

Except that's not quite the case, as it rarely ever is when a scientific story hits the news. Whether its the BBC, online science blogs or your tabloid newspaper of preference, all of these news outlets are competing for your attention and are striving to be the first to break the story. 

I won't go through the study myself, because I'm about to point you to two excellent sources that have already done a brilliant job of it, but there are a few things I want people to clearly see:

  • This is quite an early study and the failure rate of drugs that have reached this stage is still high, especially in Alzheimer's


  • It's primary aim is to show the safety and tolerability of the drug, it is not designed to give clear evidence about its effects on cognition, as the cognitive measurements were clearly listed as "exploratory"

So where can you go to find trustworthy information about science in the news? 

This can be quite difficult, especially depending on the subject, but the NHS has a special Behind the Headlines section which often does an excellent job of giving you the information you need, along with the explanation of how it fits into the rest of the scientific picture. 

Their article on the Aducanumab drug trial is available here

For this specific news article, I would recommend you read this excellent article by my old course-mate for Alzheimer's Research UK

In future you might want to check out healthnewsreviews.org which has a team of experts that voluntarily review health news stories and press releases.
You might also want to try and access the original scientific paper. These are often more balanced and cautious than the media coverage itself, but journals often require a subscription or some other form of payment to access the full papers. In future you will see more and more journals that make their articles free to anyone (called open access), but the most prestigious journals that hold most of the major stories still require payment. 

Alternatively, if you just want to know more about the set up of a clinical trial, rather than the results, you can check clinical trials databases such as clinicaltrials.gov or EU clinical trials register. You may need to find the clinical trial number in order to find the study you're looking for though.

If you do decide to read scientific papers or clinical trials databases for yourself, health news reviews has a good section for Tips for Understanding Studies. Wherever you get your science news from though, it's always a good idea to try and look a little bit deeper. 


Comments

Popular posts from this blog

Medical Writing: Do you need a PhD?

When I was looking into becoming a medical writer, I was just at the end of my MSc and trying to decide whether to try and get a job in medical communications or to do a PhD and then move into Med Comms later. The short answer is no you don't necessarily need  a PhD to be a medical writer, but some employers think you do and it certainly seems to be the ideal.  After looking around on the internet I found a few forum posts asking about the same thing, "should I do a PhD to get into Med Comms?”. Most people said no not necessarily. But as far as I could tell, all of them did have PhD’s and were just telling people well maybe yes and maybe no. Since getting a job as an associate medical writer without a PhD, I've heard a lot more of this conversation occurring within the industry and especially at careers fairs. A lot of people  do  have PhD’s and quite often post-doctoral experience. But that is normally because they started out in academia and then discovered medical w

#ThanksToVideoGames shows Twitter gaming community has a sincere side

National Video Games Day was Thursday 7th July, 2020. A day where people in the gaming community can reflect on what video games mean to them. For me, video games are a way of staying in touch with friends I no longer live close to and provides an escape from the everyday stresses of the world.  It's clear that I'm not the only one, with #ThanksToVideoGames making waves on Twitter, people from all over the world shared their own reasons to be grateful for having video games in their lives. My curiosity got the better of me; I wanted to find out more about why people were grateful for video games and I wanted to show people that (shockingly) gamers can also be very sincere online.  I created this visualisation of the most common words that appeared in tweets with #ThanksToVideoGames to show the different themes coming through in discussions on Twitter. Make sure you hit the full screen icon to show the full picture; you  c

Are We Ignoring Our Body Clocks?

The body clock (or circadian rhythm) is a system of smaller cellular clocks that is responsible for our daily cycles, we have peaks and troughs in almost all aspects of our biology, including alertness and stress. This rhythm is tuned to the day/night cycle, and helps to make sure our bodies are prepared for the behaviours that are appropriate for that time of day eg becoming sleepy when it gets dark.  However, recent research suggests that our 24/7 society is causing an increasing number of us to become out of sync with our natural rhythm and that this may be having adverse effects on our physical health and mental well-being. All animals, in fact all cells as far as I'm aware, have an internal clock. these cellular clocks are controlled by a larger network of cellular clocks in the brain, called the suprachiasmatic nucleus (SCN). this cluster of cells is kept in harmony by the day/light cycle. Using ancestral light receptors in our eyes called retinal ganglion cells, they det